The gut microbiome is the community of microorganisms living in the gut. Certain fibres can be broken down by gut bacteria and used as a source of nutrition. This process produces substances including short-chain fatty acids.

Responses to fibre vary between individuals and depend on the type of fibre. Nuvante intends to investigate how Nuvacal relates to changes in the gut microbiome and gastrointestinal tolerance. A beneficial change in specific gut bacteria resulting from the use of Nuvacal has not yet been established.